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Evolving perspectives on autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 26 September 2013, Catherine Lord and Steven Hyman presented conceptual frameworks for autism diagnosis and research, ranging from genetics to symptomatology, as part of SFARI’s Autism: Emerging Concepts lecture series. Eric London provided post-lecture commentary, placing the discussion in a clinical context and providing a physician’s perspective. You can watch a complete video...

Infants’ grasp of others’ intentions

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 6 November 2013, Amanda Woodward discussed the origins of children’s social understanding and how this fundamental aspect of cognition has profound implications for early childhood development. The talk is part of SFARI’s Autism: Emerging Concepts lecture series. Kevin Pelphrey provided post-lecture commentary on how our growing understanding of the origins of children’s social...

Imaging early brain development in autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

On 26 February, David Amaral presented evidence supporting the concept that there are different types of altered brain development among children with autism.His talk is part of SFARI’s Autism: Emerging Concepts lecture series. You can watch a complete video recording of the event above. About the lecture: Autism clearly involves altered function of the central...

An attempt at redefining autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 26 March, Ami Klin presented data from two studies measuring social adaptive behaviors — highly conserved and early-emerging mechanisms of socialization — in infants and toddlers.His talk is part of SFARI’s Autism: Emerging Concepts lecture series. You can watch a complete video recording of the event above. About the lecture: Advances in molecular...

New approaches to treating Rett syndrome

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 23 April, Gail Mandel presented the complex pathology of Rett syndrome and discussed whether this autism-related disorder would be amenable to gene replacement strategies. Her talk was part of the Simons Foundation Autism Research lecture series. You can watch a complete video recording of the event above. About the Lecture A central goal...

The social brain: Understanding autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 23 September, Nancy Kanwisher discussed the functional architecture of the social brain as an avenue for considering which functions are affected and which are preserved in autism.Her talk was part of SFARI’s Autism: Emerging Concepts lecture series. About the lecture: Humans are a highly social species, allocating numerous brain regions to distinct aspects...

Microbiota and the host immune system in autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 29 October 2014, Dan Littman described how intestinal bacteria affect immune system cell functioning, potentially contributing to systemic inflammation and autism. His talk was part of SFARI’s Autism: Emerging Concepts lecture series. About the lecture: Our immune system is heavily influenced by microbiota — the microbes that reside within us. In the intestine,...

Learning to move

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 3 December 2014, Karen E. Adolph discussed how infants learn to generate and control their movements by adapting to environmental and social factors.Her talk, which covered ways in which a variety of external factors affect how infants learn to move, was part of SFARI’s Autism: Emerging Concepts lecture series. Adolph explained how infants...

Prevalence and trends in epidemiology of autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 25 March 2015, Maureen Durkin discussed trends in the prevalence of autism and explored some of the reasons underlying the recent rise in autism cases. Her talk was part of the Simons Foundation Autism Research lecture series. About the Lecture Once considered an extremely rare childhood mental disorder, autism is now recognized as...

Timing mechanisms of critical periods in brain development

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 30 September 2015, Takao Hensch discussed the biological bases of critical periods in brain development. Mechanisms that open and close windows of plasticity (E/I balance and molecular brakes, respectively) have been implicated in autism, suggesting mistimed maturational processes that can be strategically rescued at the circuit level. His talk was part of the...

SFARI Society for Neuroscience 2015 Social

Hyatt Regency Chicago Downtown Regency Ballroom A 151 E Upper Wacker Dr, Chicago, IL, United States

  All Society for Neuroscience (SfN) attendees are welcome to join SFARI Investigators and scientific staff for an evening of socializing and networking, including a brief information session on SFARI funding programs and scientific resources for the autism research community. We welcome newcomers to autism research as well as those already working to uncover the...

Molecular and neural architecture of circuits underlying social behavior in the mouse

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 28 October 2015, Catherine Dulac discussed the cellular and molecular architecture of neural circuits underlying instinctive social behaviors in mice. Her talk was part of the Simons Foundation Autism Research lecture series. About the Lecture Severe mental disorders such autism spectrum disorders, schizophrenia and major depressive disorder are characterized by profound social impairments. There...

Storming the ivory tower: How to make autism interventions work in schools

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 11 November 2015, David S. Mandell talked about why autism interventions rarely are implemented in community practice and why they fail to achieve the same outcomes as those observed in clinical trials. His talk was part of the Simons Foundation Autism Research lecture series. About the Lecture A growing body of research shows...

Making up your mind: Interneurons in development and disease

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 27 January 2016, Gordon Fishell described his investigations of the developmental and genetic origins of interneuron development. His talk was part of the Simons Foundation Autism Research lecture series. About the Lecture Interneurons within the brain, in the cortex and hippocampus in particular, are central for normal brain function, and conversely, dysfunction of...

Development begins before birth: Prenatal research relevant to autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 30 March 2016, Catherine Monk described her lab’s fetal origins of adult disease (FOAD) studies that focus on women in the perinatal period and fetal and infant neurobehavioral development, including direct studies of the fetus, newborn brain imaging and placental methylation. Her talk was part of the Simons Foundation Autism Research lecture series....

One brain, many genomes: Somatic mutation and genomic variability in human cerebral cortex

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 27 April 2016, Christopher Walsh reviewed recent work on ‘somatic mutations’ — de novo mutations that are present in some brain cells but not in all cells of the body — in several neurological conditions associated with intellectual disability and seizures. His talk was part of the Simons Foundation Autism Research lecture series....

Sleep in autism spectrum disorders: A window to etiology, diagnosis and treatment

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 7 September 2016, Ruth O'Hara discussed the field’s current understanding of sleep in autism spectrum disorder. Her talk was part of the Simons Foundation Autism: Emerging Concepts lecture series. About the Lecture Understanding sleep physiology in autism spectrum disorder (ASD) not only provides a window to the underlying etiology, it can also help...

Tuberous Sclerosis: Shedding light on the neural circuitry of autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 5 October 2016, Mustafa Sahin presented an update on translational research in Tuberous Sclerosis Complex. His talk was part of the Simons Foundation Autism Research lecture series. About the Lecture In this lecture, Mustafa Sahin presented the rationale for investigating Tuberous Sclerosis Complex (TSC) as a way to understand the cellular and circuitry...

How immune cells help wire the brain: Implications for autism and psychiatric illness

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 2 November 2016, Beth Stevens discussed recent work that implicates brain immune cells, called microglia, in sculpting of synaptic connections during development and their relevance to autism, schizophrenia and other brain disorders. Her talk was part of the Simons Foundation Autism Research lecture series. About the Lecture Recent research has revealed a key...

SFARI Society for Neuroscience 2016 Social

Hilton San Diego Bayfront Indigo 204 One Park Blvd, San Diego, CA, United States

  All Society for Neuroscience (SfN) attendees are welcome to join SFARI Investigators and scientific staff for an evening of socializing and networking, including a brief information session on SFARI funding opportunities and scientific resources for the autism research community. We welcome newcomers to autism research as well as those already working to uncover the...

Potholes and progress on the road to translational treatments in autism spectrum disorder

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 25 January 2017, Jeremy Veenstra-VanderWeele outlined critical challenges to translating genomic, cellular, and animal model research into new treatments for autism spectrum disorder. His talk was part of the Simons Foundation Autism Research lecture series. About the Lecture Emerging genomic and neuroscience findings have delivered hypotheses that are now being tested in autism...

Exploiting genetics to identify environmental risks for autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 22 February 2017, Mark Zylka described how candidate environmental risk factors for autism can be identified rationally, by pinpointing chemicals that interfere with the same molecular pathways that are affected in individuals with autism. His talk was part of the Simons Foundation Autism Research lecture series. About the Lecture Our inability to identify...

What can genetics tell us about autism spectrum disorder?

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 22 March 2017, Stephan Sanders presented an update on the current state of genetics research in autism, highlighting some of the key findings that remain to be discovered, and discussing how these findings could ultimately benefit individuals with autism and their families. His talk was part of the Simons Foundation Autism Research lecture...

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SFARI Society for Neuroscience 2017 Social

Marriott Marquis Washington, D.C. Liberty Salons I, J, K 901 Massachusetts Ave NW, Washington, D.C., United States

  All Society for Neuroscience (SfN) attendees are welcome to join SFARI Investigators and scientific staff for an evening of socializing and networking, including a brief information session on SFARI funding opportunities and scientific resources for the autism research community. We welcome newcomers to autism research as well as those already working to uncover the...

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