To ensure that our funding is as impactful as possible, SFARI will be undergoing a strategic planning process in the first half of 2024. We have thus adjusted our request for applications (RFA) schedule to ensure that the SFARI science team can devote sufficient time and energy to this effort. In 2024, we will hold the Bridge to Independence (BTI) RFA, and one call for Pilot Awards, in tandem with a call for continuation funding for former Pilot or BTI Award grantees whose projects have been successful. We will also hold a targeted RFA on Bridging Early Neurodevelopment and Emerging Neural Circuits, as well as a call for proposals for an updated version of SFARI Gene.
We solicit applications for SFARI Awards from individuals who will conduct bold, imaginative, rigorous and relevant research in four main research areas: gene discovery, molecular mechanisms, circuits, cognition and behavior, and clinical.
Two studies by different research groups — one led by Flora Vaccarino and the other by Juergen Knoblich — used brain organoids derived from pluripotent stem cells of people with autism and showed how transcriptional alterations affecting certain cell types during human brain development could contribute to the early emergence of ASD.
In a mouse model of fragile X syndrome, Emily Osterweil and her colleagues show that excessive protein synthesis drives a pathological compensatory rise in protein degradation (by the ubiquitin proteasome system), which can be targeted to correct various phenotypes including audiogenic seizures.
A study by Caroline Robertson and her colleagues found that reduced social attention was not a static omnipresent characteristic of autism; rather, it was magnified only under certain real-world conditions where sensory processing demands were high.
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March 7, 2023
On March 7, 2023, SFARI held an informational session about the 2022 Human Cognitive and Behavioral Science request for applications (RFA)
January 10, 2022
SFARI hosted an informational session on the 2022 Bridge to Independence Award (BTI) request for applications (RFA). The session provided a brief overview of the BTI program...
May 14, 2021
Federico Bolognani, Stuart Cobb, and Yael Weiss joined a panel to discuss new industry developments on the use of small molecules, gene therapy and antisense oligonucleotides...
May 12, 2021
Jake Gratten and Naomi Wray presented findings from the Australian Autism Biobank study, an initiative to establish an Australian resource of biospecimens, phenotypes and...