New research results from the Australian Autism Biobank study

  • Speakers
  • Jake Gratten, Ph.D.

    Group Leader, Mater Research Institute, The University of Queensland
    Adjunct Senior Research Fellow, Institute for Molecular Bioscience

    Naomi Wray, Ph.D.

    National Health and Medical Research Council Leadership Fellow – Group Leader, Institute for Molecular Bioscience
    Affiliate Professor, Queensland Brain Institute, The University of Queensland

Date & Time


Location

Webinar

Schedule
4:45 – 5:00 PM ET
Waiting room opens

5:00 – 6:15 PM
ET Talk + Q&A

 

Speakers
Jake Gratten, Ph.D.
University of Queensland

Naomi Wray, Ph.D.
University of Queensland

New research results from the Australian Autism Biobank study

On May 12, 2021, Jake Gratten and Naomi Wray will present findings from the Australian Autism Biobank study, an initiative to establish an Australian resource of biospecimens, phenotypes and genomic data for autism research.

Their talk is part of the Simons Foundation Autism Research lecture series.

About the Lecture

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition whose biological basis is yet to be elucidated. The Australian Autism Biobank (AAB) is an initiative of the Cooperative Research Centre for Living with Autism to establish an Australian resource of biospecimens, phenotypes and genomic data for autism research.

In this lecture, Jake Gratten and Naomi Wray will report on results from 2,477 individuals with DNA data from 546 families, including 886 participants ages 2 to 17 years with diagnosed (871 participants) or suspected (15 participants) ASD, 218 siblings without ASD, 1,256 parents, and 117 unrelated children without an ASD diagnosis. A subset of these AAB participants has fecal microbiome data (the largest data set to date internationally). Their analyses suggest that autism traits lead to restricted dietary intake, leading to reduced microbiome diversity, with no evidence for a reverse causal relationship.

Registration is required for this free event.

Further instructions and access to join the webinar will be sent to all registrants upon sign up.

Inquiries: lectures@simonsfoundation.org 

About the Speakers

Jake Gratten leads the Cognitive Health Genomics group at the Mater Research Institute at the University of Queensland in Australia. He is a former National Health and Medical Research Council Career Development Fellow, and he leads systems genomics analyses of autism for the Australian Autism Cooperative Research Centre. His research aims to understand the causes of common brain disorders by combining cutting-edge laboratory methods with statistical analysis of large-scale genomic, psychometric and lifestyle data.

Naomi Wray holds joint professorial positions between the Institute for Molecular Bioscience and the Queensland Brain Institute at The University of Queensland in Australia. She is a fellow of the Australian Academy of Science and a fellow of the Australian Academy of Health and Medical Sciences. Her research intersects quantitative genetics, statistical methodology and disorders of the brain. She has played leading roles in analyses for International Psychiatric Genomics Consortia working groups.

Past Lectures

Rare variants and the genetics of autism

Evan E. Eichler, Ph.D.Professor, Department of Genome Sciences and Howard Hughes Medical Institute, University of Washington, Seattle

Evan Eichler discussed his research on the genetics of autism and related neurodevelopmental conditions.

Phenotyping sleep

Emmanuel Mignot, M.D., Ph.D.Craig Reynolds Professor of Sleep Medicine, Stanford University

Emmanuel Mignot discussed sleep biology as well as sleep disorders and their impact. He presented a link to what is known on the genetics of sleep and sleep disorders. He emphasized the need for large scale objective sleep recording studies with genomic and proteomic analysis to better understand the molecular pathways regulating sleep and circadian biology.

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