SFARI is working to advance autism science by providing a number of key resources to researchers. These include:
- Cohorts of well-characterized individuals with autism or with specific genetic alterations, including the Simons Simplex Collection (SSC), the Simons Variation in Individuals Project (Simons VIP), Simons Foundation Powering Autism Research for Knowledge (SPARK) and the Autism Inpatient Collection (AIC).
- Tools that enable researchers to keep track of the genetic risk factors for autism (SFARI Gene).
- Data (including clinical, phenotypic, genetic, and neuroimaging data) and biospecimens from SFARI collections and SFARI-funded projects (SFARI Base).
- Tools that enable researchers to explore data from the SSC, Simons VIP and SPARK, including the WuXi NextCODE SSC portal, the Genotypes and Phenotypes in Families online platform, SFARI Viewer and the Beacon Network.
- Induced pluripotent stem cell lines from SSC and Simons VIP participants.
- Autism mouse models that are readily available for researchers to order from The Jackson Laboratory.
- Autism rat models that are readily available for researchers to order from the Medical College of Wisconsin.
- Postmortem brain tissue for autism research (available through the collaborative network, Autism BrainNet).
- Therapeutics, including arbaclofen, for investigator-initiated studies in humans and animals (available from Clinical Research Associates, L.L.C., an affiliate of the Simons Foundation).