Thinking differently about neurodevelopmental disorders and autism: Lumping vs. splitting

  • Autism Research
Speaker Evdokia Anagnostou, M.D.
Bloorview Research Institute
Date & Time


Location

Gerald D. Fischbach Auditorium
160 5th Avenue
New York, NY 10010 United States

Tea: 4:15 – 5:00pm
Lecture: 5:00 – 6:15pm

Autism Research

Autism Research lectures bring together scientists and scholars to discuss diverse and important topics related to autism. The lectures are open to the public and are held at the Gerald D. Fischbach Auditorium at the Simons Foundation headquarters in New York City. Tea is served prior to each lecture.

Video replay of this event will be available shortly. Please check back at a later date.

On September 26, 2018, Evdokia Anagnostou discussed the challenge of rethinking classification systems and diagnostic labels for autism and related neurodevelopmental disorders in light of recent findings from research and clinical studies.

Her talk was part of the Simons Foundation Autism Research lecture series.

About the Lecture

There has been an explosion of discoveries furthering our understanding of the biology and the various presentations of autism spectrum disorder and other neurodevelopmental differences. The excitement from the new understandings is matched by the challenge to rethink our classification systems and diagnostic labels and translate that into meaningful treatments.

In this lecture, Evdokia Anagnostou used evidence from genetics, brain imaging and behavior as well as treatment studies to illustrate this emerging rethinking of neurodevelopmental conditions.

About the Speaker

Evdokia Anagnostou is a child neurologist and senior clinician scientist at Holland Bloorview Kids Rehabilitation Hospital; associate professor in the Department of Pediatrics at the University of Toronto; assistant director of the Bloorview Research Institute and co-lead of the Autism Research Centre. She holds a Canada Research Chair in translational therapeutics in autism spectrum disorder and the Dr. Stuart D. Sims Chair in Autism at Holland Bloorview Kids Rehabilitation Hospital.

Anagnostou’s research focuses on translating genomic and systems biology findings into novel treatments for autism spectrum disorder.

Past Lectures

The genetic influences on autism spectrum disorder risk

Elise Robinson, Sc.D.Assistant Professor, Harvard T.H. Chan School of Public Health
Associate Member, Broad Institute

On January 30, 2019, Elise Robinson provided an overview of the role that genetic factors play in autism spectrum disorders and discussed the next steps to further understand autism genetics.

The predictive impairment hypothesis in autism: An empirical assessment

Pawan Sinha, Ph.D.Professor, Massachusetts Institute of Technology
Dagmar Sternad, Ph.D.Professor, Northeastern University

On December 12, 2018, Pawan Sinha and Dagmar Sternad reviewed a recently proposed hypothesis about the nature of autism spectrum disorders (ASD) that posits that the common traits of the disorder are manifestations of an individual’s difficulty in making predictions about cause and effect.

Rethinking autism and animal models: A systems perspective

André Fenton, Ph.D.Professor, Center for Neural Science, New York University

On November 28, 2018, André Fenton discussed work with mouse genetic models of fragile X syndrome (FXS) – the most common single-gene cause of autism spectrum disorder (ASD) symptoms – and focused on the utility of such models to evaluate hypotheses for understanding ASD. He evaluated distinct hypotheses by assessing synapse function and the action potential discharge of knowledge-expressing hippocampus “place cells” during behaviors that require varying cognitive effort.

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