Altered somatosensory processing in autism spectrum disorders: Mechanisms and emerging therapeutic opportunities

  • Autism Research
Speaker David Ginty, Ph.D.
Harvard University
Date & Time


Location

Gerald D. Fischbach Auditorium
160 5th Avenue
New York, NY 10010 United States

Tea 4:15 – 5:00 pm
Lecture 5:00 – 6:15 pm

Autism Research

Autism Research lectures bring together scientists and scholars to discuss diverse and important topics related to autism. The lectures are open to the public and are held at the Gerald D. Fischbach Auditorium at the Simons Foundation headquarters in New York City. Tea is served prior to each lecture.

Video replay of this event will be available shortly. Please check back at a later date.

On April 24, 2019, David Ginty presented his work on the neurobiological basis of touch over-reactivity in mouse models of autism spectrum disorders (ASD). He also discussed new pharmacological approaches aimed at reducing sensory over-reactivity and potentially improving cognitive and behavioral abnormalities associated with ASD.

His talk was part of the Simons Foundation Autism Research lecture series.

About the Lecture

Mounting evidence indicates that sensory processing impairments are a key feature of ASD. In this lecture, David Ginty described work that employs molecular genetics, electrophysiological, synaptic and behavioral analyses to define the neurobiological basis of touch over-reactivity in mouse models of ASD, and its relationship to brain development and ASD-associated behavior. He also discussed new pharmacological approaches to treat touch over-reactivity with the goal of reducing sensory over-reactivity and potentially improving cognitive and behavioral abnormalities associated with ASD.

About the Speaker

David Ginty is the Edward R. and Anne G. Lefler Professor of Neurobiology at Harvard Medical School and an investigator of the Howard Hughes Medical Institute. His research focuses on development and functional organization of neural circuits that underlie touch perception in normal and disease states, and he serves as associate director of Harvard’s Program in Neuroscience. Ginty is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences.

Past Lectures

Altered somatosensory processing in autism spectrum disorders: Mechanisms and emerging therapeutic opportunities

David Ginty, Ph.D.Professor of Neurobiology, Harvard University

On April 24, 2019, David Ginty presented his work on the neurobiological basis of touch over-reactivity in mouse models of autism spectrum disorder (ASD). He also discussed new pharmacological approaches aimed at reducing sensory over-reactivity and potentially improving cognitive and behavioral abnormalities associated with ASD.

Mapping human cerebral cortex: Structure, function, connectivity, development and evolution

David Van Essen, Ph.D.Alumni Endowed Professor , Washington University in St. Louis

On April 3, 2019, David Van Essen provided an overview of basic principles of cortical organization and connectivity from studies of laboratory animals and analyses of individual variability in humans. He also highlighted a new map (‘parcellation’) of the human cerebral cortex based on data from the Human Connectome Project.

The genetic influences on autism spectrum disorder risk

Elise Robinson, Sc.D.Assistant Professor, Harvard T.H. Chan School of Public Health
Associate Member, Broad Institute

On January 30, 2019, Elise Robinson provided an overview of the role that genetic factors play in autism spectrum disorders and discussed the next steps to further understand autism genetics.

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