Individuals with autism spectrum disorder experience difficulty integrating across sensory modalities, such as sight and sound. Multisensory integration is particularly prevalent in the subcortical superior colliculus, yet studies to date have not investigated its potential contributions to ASD. In this study, Feinberg plans to test the hypothesis that superior colliculus multisensory integration is altered in mouse models of ASD.
Ginty will define the mechanisms of aberrant touch sensitivity in mouse models of ASD and in individuals with ASD, and will translate these findings into possible therapeutics.
SFARI Investigator Liqun Luo discusses the neurodevelopmental disorder Smith-Magenis syndrome and his lab’s efforts to understand its underlying biology.
SFARI is pleased to announce that it has awarded 14 grants over the past year in response to the Explorer Awards request for applications.
SFARI is pleased to announce that it has awarded 27 grants (21 Pilot Awards and 6 Research Awards) in response to the 2016 Pilot and Research Awards request for applications.
Rudolf Jaenisch has developed a method enabling the generation of microglia-like cells from human embryonic stem cells and induced pluripotent stem cells.