Lonnie Zwaigenbaum, M.D.

Professor, University of Alberta

SFARI Investigator, SFARI Scientific Review Board Website

Lonnie Zwaigenbaum is a professor and the director of autism research in the division of Developmental Pediatrics in the Faculty of Medicine & Dentistry at the University of Alberta. Zwaigenbaum completed his pediatric training at Queen’s University and his clinical fellowship in developmental pediatrics at the Hospital for Sick Children in Toronto. He completed a research fellowship and master’s degree in health research methodology at McMaster University.

His research focuses on early behavioral and biological markers, and early developmental trajectories in children with autism and related disorders. To identify early behavioral and neurobiological markers of autism, his research group is following a high-risk cohort, namely infant siblings of children with autism, in order to identify specific risk markers to aid in earlier diagnosis and study basic processes (e.g., attention, emotion, executive control) that may underlie later symptoms.

Funded Projects

Genomic influences on development and outcomes in infants at risk for autism

Awarded: 2011
Award Type: Research

SFARI Funded Publications

Genomic architecture of autism spectrum disorder from comprehensive whole-genome sequence annotation. Trost B., Thiruvahindrapuram B., Chan A.J.S., Engchuan W., Higginbotham E.J., Howe J.L., Loureiro L.O., Reuter M.S., Roshandel D., Whitney J., Zarrei M., Bookman M., Somerville C., Shaath R., Abdi M., Aliyev E., Patel R.V., Nalpathamkalam T., Pellecchia G., Hamdan O., Kaur G., Wang Z., MacDonald J.R., Wei J., Sung W.W.L., Lamoureux S., Hoang N., Selvanayagam T., Deflaux N., Geng M., Ghaffari S., Bates J., Young E.J., Ding Q., Shum C., D'abate L., Bradley C.A., Rutherford A., Aguda V., Apresto B., Chen N., Desai S., Du X., Fong M.L.Y., Pullenayegum S., Samler K., Wang T., Ho K., Paton T., Pereira S.L., Herbrick J.-A., Wintle R.F., Fuerth J., Noppornpitak J., Ward H., Magee P., Al Baz A., Kajendirarajah U., Kapadia S., Vlasblom J., Valluri M., Green J., Seifer V., Quirbach M., Rennie O., Kelley E., Masjedi N., Lord C., Szego M.J., Zawati M.H., Lang M., Strug L.J., Marshall C.R., Costain G., Calli K., Iaboni A., Yusuf A., Ambrozewicz P., Gallagher L., Amaral D., Brian J., Elsabbagh M., Georgiades S., Messinger D.S., Ozonoff S., Sebat J., Sjaarda C.P., Smith I.M., Szatmari P., Zwaigenbaum L., Kushki A., Frazier T., Vorstman J.A.S., Fakhro K.A., Fernandez B.A., Lewis M.E.S., Weksberg R., Fiume M., Yuen R.K.C., Anagnostou E., Sondheimer N., Glazer D., Hartley D.M., Scherer S. W.

Examining the factor structure and discriminative utility of the infant behavior questionnaire-revised in infant siblings of autistic children. Sung S., Fenoglio A., Wolff J.J., Schultz R., Botteron K., Dager S., Estes A.M., Hazlett H., Zwaigenbaum L., Piven J., Elison J.T., IBIS Network

Infant vocalizing and phenotypic outcomes in autism: Evidence from the first 2 years. Plate S., Yankowitz L., Resorla L., Swanson M.R., Meera S.S., Estes A., Marrus N., Cola M., Petrulla V., Faggen A., Pandey J., Paterson S., Pruett J.R. Jr., Hazlett H., Dager S., St. John T., Botteron K., Zwaigenbaum L., Piven J., Schultz R., Parish-Morris J., IBIS Network