Thomas Frazier is a licensed clinical psychologist who received his Ph.D. from Case Western Reserve University in 2004. He joined the Cleveland Clinic in 2006 and was the director of the Cleveland Clinic Center for Autism from 2013 to 2017. In 2017, he was hired as the Chief Science Officer at Autism Speaks. He is also a professor of psychology at John Carroll University.

Over the last decade, Frazier has maintained an active clinical practice and research programs focused on the evaluation and treatment of autism. His work is focused on the development of new measures to improve the assessment of autism and related genetic syndromes and to better understand individuals with PTEN mutations and neurodevelopmental disorders.