

Funded Projects
CRISPR activation-based approach to rescue cellular and behavioral deficits associated with Scn2a haploinsufficiency
Awarded: 2019
Award Type: Director
Award Type: Director
Cellular and circuit effects of SCN2A haploinsufficiency
Awarded: 2017
Award Type: Pilot
Award Type: Pilot
Electrophysiological consequences of SCN2A mutations found in autism
Awarded: 2015
Award Type: Explorer
Award Type: Explorer
SFARI Funded Publications
CRISPR activation rescues abnormalities in SCN2A haploinsufficiency-associated autism spectrum disorder.
Tamura S., Nelson A.D., Spratt P.W.E., Kyoung H., Zhou X., Li Z., Zhao J., Holden S.S., Sahagun A., Keeshen C.M., Lu C., Hamada E.C., Ben-Shalom R., Pan J.Q., Paz J.T., Sanders S., Matharu N., Ahituv N., Bender K.
LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants.
Darbandi S.F., Nelson A.D., Pai E.L., Bender K., Rubenstein J.