Alfred George is the Magerstadt Professor of Pharmacology, chair of the Department of Pharmacology and director of the Center for Pharmacogenomics at Northwestern University Feinberg School of Medicine.
He has over 30 years of experience investigating the structure, function, molecular genetics and pharmacology of human ion channels and transporters. He is an internationally regarded leader in the field of channelopathies, including paroxysmal disorders of the heart, brain and neuromuscular system.
George has a unique blend of expertise in human genetics, ion channel biology and pharmacology. His laboratory at Northwestern University installed the first gigaseal-capable 384-well automated electrophysiology platform in the United States and has demonstrated a high level of proficiency in using this system for high-throughput functional evaluations of human ion channel variants. These capabilities will be harnessed to achieve the goals of the proposed research to assess SCN2A variants associated with autism.