This year’s new cohort of National Academy of Medicine members includes two investigators funded by the Simons Foundation Autism Research Initiative (SFARI). Election to the academy “recognizes individuals who have demonstrated outstanding professional achievement and commitment to service.”
Menglong Zeng received his doctoral training in Mingjie Zhang’s lab at the Hong Kong University of Science and Technology, where he applied biochemistry and structural biology to investigate how synaptic proteins interact to regulate synapse function.
Recent technological advances have identified many ASD risk genes, but how these genes affect brain development and function remains unknown, especially in primates. In the current project, Xinyu Zhao, Qiang Chang, André Sousa and Daifeng Wang plan to genetically manipulate three ASD risk genes in marmoset brain slices followed by multimodal integrative analysis of electrical activities, gene expression and chromatin accessibility of single neurons in the prefrontal cortex. The results will provide new and in-depth knowledge of the neuronal functions of these genes in primate brains.
SFARI is pleased to announce that it intends to fund 15 grants in response to the 2022 Genomics of ASD: Pathways to Genetic Therapies request for applications.
SFARI is pleased to announce that it intends to fund 16 grants in response to the 2022 Pilot Award request for applications.
SFARI is pleased to announce that it has selected seven fellows in response to the 2022 Bridge to Independence Award request for applications.
Michael Segel is a postdoctoral fellow at the Broad Institute of MIT and Harvard. He received his A.B. from Harvard College in human developmental and regenerative biology and his Ph.D. in clinical neuroscience from the University of Cambridge. For his doctoral thesis in the lab of Robin Franklin, he explored the molecular mechanisms underpinning the aging of glia in the central nervous system.
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