Jay Gibson, Ph.D.

Associate Professor of Neuroscience, University of Texas Southwestern Medical Center

SFARI Investigator Website

Jay Gibson is an associate professor of neuroscience at the University of Texas (UT) Southwestern Medical Center in Dallas, Texas. As an undergraduate, Gibson studied biophysics at the University of California, Berkeley. Under the guidance of John Maunsell, he completed his Ph.D. at the University of Rochester, which focused on neocortical activity related to visual processing. Next, he worked under Barry Connors, studying the electrophysiological properties of inhibitory interneurons in the somatosensory cortex.

Gibson joined the Department of Neuroscience at UT Southwestern in 2001. Currently, his laboratory uses electrophysiological techniques to study the development of cortical circuits and their alterations in mouse models of autism spectrum disorder.

Funded Projects

Foxp1-regulated cell-type specific contributions to striatal development in mice

Awarded: 2018
Award Type: Research

FOXP1 orchestration of neuronal function in the striatum

Awarded: 2016
Award Type: Pilot

SFARI Funded Publications

FOXP1 negatively regulates intrinsic excitability in D2 striatal projection neurons by promoting inwardly rectifying and leak potassium currents. Khandelwal N., Cavalier S., Rybalchenko V., Kulkarni A., Anderson A.G., Konopka G., Gibson J.

Experience-dependent and differential regulation of local and long-range excitatory neocortical circuits by postsynaptic Mef2c. Rajkovich K.E., Loerwald K.W., Hale C.F., Hess C.T., Gibson J., Huber K.

Research Highlight

A role for dendritic mGluR5-mediated local translation of ARC/ARG3.1 in MEF2-dependent synapse elimination. Wilkerson J.R., Tsai N., Maksimova M.A., Wu H., Cabalo N.P., Loerwald K.W., Dictenberg J.B., Gibson J., Huber K.