Autism Research lectures bring together scientists and scholars to discuss diverse and important topics related to autism.
On 25 April 2013, Matthew State reviewed the genetic discoveries made over the past several years in autism research and addressed challenges in the path forward — from reliable gene discovery to an actionable understanding of the disorder’s molecular underpinnings.
The talk is part of the Simons Foundation Autism Research lecture series. You can watch a complete video recording of the event above. Use the comments section below to discuss the lecture and pose follow-up questions.
The genetics of autism has reached a tipping point. The recent focus on de novo mutations — or genetic variations not passed on from either parent — has led to systematic, highly productive gene discovery efforts. This work has begun to clarify a tremendously heterogeneous genetic architecture as well as to reveal specific genes contributing to social disability syndromes.