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On 25 April 2013, Matthew State reviewed the genetic discoveries made over the past several years in autism research and addressed challenges in the path forward — from reliable gene discovery to an actionable understanding of the disorder’s molecular underpinnings.
The talk is part of the Simons Foundation Autism Research lecture series. You can watch a complete video recording of the event above. Use the comments section below to discuss the lecture and pose follow-up questions.
About the Lecture
The genetics of autism has reached a tipping point. The recent focus on de novo mutations — or genetic variations not passed on from either parent — has led to systematic, highly productive gene discovery efforts. This work has begun to clarify a tremendously heterogeneous genetic architecture as well as to reveal specific genes contributing to social disability syndromes.