Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing.
Molecular Mechanisms
Single-cell transcriptome identifies molecular subtype of autism spectrum disorder impacted by de novo loss-of-function variants regulating glial cells.
Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids.
Biophysical Kv3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer’s.
Macrophages on the margin: Choroid plexus immune responses.
A transcriptional constraint mechanism limits the homeostatic response to activity deprivation in mammalian neocortex.
Altered inflammatory response in FMRP-deficient microglia.
Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity.
Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration.
Single-cell epigenomics reveals mechanisms of human cortical development.
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