Tag: CHD8

November 14, 2022

Developing Rat MoSeq to characterize autism models

August 31, 2022

New DYRK1A and GRIN2B zebrafish models added to SFARI resources

August 01, 2022

Anomalous visual integration in mouse models of autism

June 28, 2022

Functional annotation of gene variants in autism risk genes using DNA methylation signatures

January 28, 2022

Simons Searchlight: December 2021 data release

December 17, 2021

SFARI 2021 Pilot awardees announced

Neuromuscular junction. Fluorescent confocal light micrograph of the junction between a nerve cell and a muscle (not seen). The axon of the nerve cell (neuron) has been tagged with a blue dye. The axon ends at end plates, which form junctions called synapses with the muscle cells. The end plates have been dyed red here by tagging them with the snake venom alpha-bungarotoxin, which binds to them. When a nerve signal reaches the synapse, it causes the synaptic vesicles to rupture, releasing the neurotransmitter acetylcholine. The protein synaptophysin, found in the vesicles, is dyed green. Acetylcholine binds to receptors on the muscle cells, causing them to contract. Magnification: x120 when printed 10cm wide.

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