Shinya Yamamoto, D.V.M., Ph.D.

Associate Professor, Baylor College of Medicine

SFARI Investigator Website

Funded Projects

In vivo functional analysis of autism candidate genes

Awarded: 2015
Award Type: Targeted: Functional Screen of Autism-Associated Variants

SFARI Funded Publications

Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases. Marcogliese P.C., Deal S.L., Andrews J., Harnish J.M., Bhavana V.H., Graves H.K., Jangam S., Luo X., Liu N., Bei D., Chao Y.-H., Hull B., Lee P.-T., Pan H., Bhadane P., Huang M.-C., Longley C.M., Chao H.-T., Chung H.-l., Haelterman N.A., Kanca O., Manivannan S.N., Rossetti L.Z., German R.J., Gerard A., Schwaibold E.M.C., Fehr S., Guerrini R., Vetro A., England E., Murali C.N., Barakat T.S., van Dooren M.F., Wilke M., van Slegtenhorst M., Lesca G., Sabatier I., Chatron N., Brownstein C.A., Madden J.A., Agrawal P.B., Keren B., Courtin T., Perrin L., Brugger M., Roser T., Leiz S., Mau-Them F.T., Delanne J., Sukarova-Angelovska E., Trajkova S., Rosenhahn E., Strehlow V., Platzer K., Keller R., Pavinato L., Brusco A., Rosenfeld J.A., Marom R., Wangler M., Yamamoto S.

Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders Guo H., Bettella E., Marcogliese P.C., Zhao R., Andrews J.C., Nowakowski T., Gillentine M.A., Hoekzema K., Wang T., Wu H., Jangam S., Liu C., Ni H., Willemsen M.H., van Bon B.W., Rinne T., Stevens S.J.C., Kleefstra T., Brunner H.G., Yntema H.G., Long M., Zhao W., Hu Z., Colson C., Richard N., Schwartz C.E., Romano C., Castiglia L., Bottitta M., Dhar S.U., Erwin D.J., Emrick L., Keren B., Afenjar A., Zhu B., Bai B., Stankiewicz P., Herman K., University of Washington Center for Mendelian Genomics, Mercimek-Andrews S., Juusola J., Wilfert A.B., Abou Jamra R., Büttner B., Mefford H., Muir A.M., Scheffer I.E., Regan B.M., Malone S., Gecz J., Cobben J., Weiss M.M., Waisfisz Q., Bijlsma E.K., Hoffer M.J.V., Ruivenkamp C.A.L., Sartori S., Xia F., Rosenfeld J.A., Bernier R., Wangler M., Yamamoto S., Xia K., Stegmann A.P.A., Bellen H.J., Murgia A., Eichler E.

In vivo functional study of disease-associated rare human variants using Drosophila. Harnish J.M., Deal S.L., Chao H.T., Wangler M., Yamamoto S.