

Funded Projects
A human stem cell-based neuronal network platform for functional validation of autism-linked variants
Awarded: 2021
Award Type: Targeted: Genomics of ASD: Pathways to Genetic Therapies
Award Type: Targeted: Genomics of ASD: Pathways to Genetic Therapies
Building phenotypic maps based on neuronal activity and transcriptional profiles in human cell models of syndromic forms of ASD
Awarded: 2019
Award Type: Pilot
Award Type: Pilot
SFARI Funded Publications
Rapid specification of human pluripotent stem cells to functional astrocytes.
Lendemeijer B., Unkel M., Mossink B., Hijazi S., Sampedro S.G., Shpak G., Slump D.E., van den Hout M.C.G.N., van IJcken W.F.J., Bindels E.M.J., Hoogendijk W.J.G., Kasri N. N., de Vrij F.M.S., Kushner S.A.
Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks.
Mossink B., van Rhijn J.-R., Wang S., Linda K., Vitale M.R., Zöller J.E.M., van Hugte E.J.H., Bak J., Verboven A.H.A., Selten M., Negwer M., Latour B.L., van der Werf I., Keller J.M., Gunnewiek T.M.K., Schoenmaker C., Oudakker A., Anania A., Jansen S., Lesch K.-P., Frega M., van Bokhoven H., Schubert D., Kasri N. N.
Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through cAMP/PKA pathway
Wang S., van Rhijn J.R., Akkouh I., Kogo N., Maas N., Bleeck A., Lewerissa E., Wu K., Schoenmaker C., Djurovic S., van Bokhoven H., Kleefstra T., Kasri N. N., Schubert D.
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