Azra Jaferi is a freelance science writer and editor. Prior to becoming a freelancer, she held in-house editorial roles at various science and technology companies, including IBM Watson Health, the New York Academy of Sciences and Medscape. Jaferi’s work as a writer and editor has been multidisciplinary, spanning topics in the basic, translational and clinical sciences. She has a B.A. in psychology from Barnard College of Columbia University and a Ph.D. in neuroscience from the University of Michigan, where her research focused on neural circuits underlying habituation to repeated stress. She did postdoctoral research in cellular neuroscience at the Brain and Mind Research Institute at Weill Cornell Medicine.
In a mouse model of fragile X syndrome, Emily Osterweil and her colleagues show that excessive protein synthesis drives a pathological compensatory rise in protein degradation (by the ubiquitin proteasome system), which can be targeted to correct various phenotypes including audiogenic seizures.
A study by Caroline Robertson and her colleagues found that reduced social attention was not a static omnipresent characteristic of autism; rather, it was magnified only under certain real-world conditions where sensory processing demands were high.
Elise Robinson and colleagues identified a large genomic region — chromosome 16p — where a rare 16p11.2 variant associated with autism functionally converges with common polygenic variation across 16p. Both rare and common genetic variation at 16p decreased expression of neuronally expressed genes, with relevance for increasing autism risk.