Phenotypic data from 310,649 participants enrolled in SPARK, including 123,444 individuals with ASD, are now available to approved researchers. Genomic data (whole-exome sequencing and genome-wide genotyping data) are also available for 81,172 SPARK participants. Of these, 3,568 genomes and 34,164 exomes are from individuals with ASD.
jesse
On August 4, 2022, SFARI and Simons Searchlight helped to host two scientific workshops focused on neurodevelopmental disorders (NDDs) that are linked to mutations in the CSNK2A1 and SETBP1 genes. Meeting in Baltimore, the workshops were held in conjunction with a family conference that gathered together people with these conditions and their family members.
This issue of the SFARI newsletter includes: (1) Updates to SFARI’s Requests for Grant Applications for 2023, (2) Important Changes to the Independence Award Program, (3) 2022 SFARI Human Cognitive and Behavioral Science Awardees Announced, (4) Event: Simons Foundation Autism and Neuroscience Social at SfN 2022, (5) 2023 Winter Pilot Award – Request for Applications.
SFARI is pleased to announce that it intends to award ten grants in response to the 2022 Human Cognitive and Behavioral Science request for applications.
Studies by two different research teams — one led by Ethan Greenblatt and the other by Emily Osterweil — both suggest that FXS cells under-synthesize large proteins, findings that suggest a new point of view on a fundamental problem.
To further our goal of funding the best and most transformative research on autism, SFARI strives to strike a balance between open requests for grant applications (RFAs) on any autism-related topic and more targeted RFAs focused on top priorities identified by SFARI. In 2023, we will hold two calls for Pilot Awards and will reissue the Human Cognitive and Behavioral Science RFA and the Genomics of ASD RFA. We will also issue a call for projects that integrate the study of ASD-relevant behaviors across human and non-human species.
SFARI is pleased to announce that it intends to fund 16 grants in response to the 2022 Pilot Award request for applications.
SFARI hosted a virtual workshop on March 14 and 18, 2022, to discuss the best practices for the development and use of induced pluripotent stem (iPS) cell models for autism research, including iPS cells generated from SFARI autism cohorts.
New zebrafish lines with mutations in the high-confidence autism risk genes DYRK1A and GRIN2B have been added to SFARI resources.
Genevieve Konopka and colleagues coupled brain imaging with measures of gene expression to reveal that gene expression patterns in the cortex that typically underlie functional brain activity in neurotypical individuals are affected in people with autism.
- Previous Page
- Viewing
- Next Page