Molecular Mechanisms

Subcellular organization of UBE3A in neurons.

TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons.

SHANK proteins: Roles at the synapse and in autism spectrum disorder.

Neuronal activity modifies the chromatin accessibility landscape in the adult brain.

The placental interleukin-6 signaling controls fetal brain development and behavior.

A cell type-specific expression signature predicts haploinsufficient autism-susceptibility genes.

TLR3 downregulates expression of schizophrenia gene DISC1 via MYD88 to control neuronal morphology.

Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism.

MECP2 regulates cortical plasticity underlying a learned behavior in adult female mice.

Retrograde synaptic inhibition is mediated by alpha-neurexin binding to the alpha2delta subunits of N-type calcium channels.

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