Molecular Mechanisms

CNTNAP4 differentially contributes to GABAergic and dopaminergic synaptic transmission.

Divergent dysregulation of gene expression in murine models of fragile x syndrome and tuberous sclerosis.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.

De novo TBR1 mutations in sporadic autism disrupt protein functions.

Interactions of innate and adaptive immunity in brain development and function.

Deterministic progenitor behavior and unitary production of neurons in the neocortex.

An AUTS2-polycomb complex activates gene expression in the CNS.

Neuron-specific regulation of class I PI3K catalytic subunits and their dysfunction in brain disorders.

An autism-linked mutation disables phosphorylation control of UBE3A.

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