Molecular Mechanisms

The 16p11.2 deletion mouse model of autism exhibits altered cortical progenitor proliferation and brain cytoarchitecture linked to the ERK MAPK pathway.

Control of brain development, function, and behavior by the microbiome.

First glimpses of the neurobiology of autism spectrum disorder.

The tumor suppressor p53 guides GluA1 homeostasis through Nedd4-2 during chronic elevation of neuronal activity.

Mapping social behavior-induced brain activation at cellular resolution in the mouse.

Diversity of transgenic mouse models for selective targeting of midbrain dopamine neurons.

Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases.

Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets.

miRNA-target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity.

The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment.

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