Molecular Mechanisms

Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development.

By hook or by crook: Multifaceted DNA-binding properties of MeCP2.

Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming.

Mitochondrial abnormalities in temporal lobe of autistic brain.

Axonal translation of beta-catenin regulates synaptic vesicle dynamics.

The ability of BDNF to modify neurogenesis and depressive-like behaviors is dependent upon phosphorylation of tyrosine residues 365/367 in the GABA(A)-receptor gamma2 subunit.

DNA Modifications and neurological disorders

Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling.

Cortical evolution: Judge the brain by its cover.

Targeting the mitochondrial electron transport chain in autism, a systematic review and synthesis of a novel therapeutic approach.

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