Molecular Mechanisms

The transcriptional regulator ADNP links the BAF (SWI/SNF) complexes with autism.

HITS-CLIP and integrative modeling define the RBFOX splicing-regulatory network linked to brain development and autism.

A role for dendritic mGluR5-mediated local translation of ARC/ARG3.1 in MEF2-dependent synapse elimination.

A novel computational biostatistics approach implies impaired dephosphorylation of growth factor receptors as associated with severity of autism.

Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus.

MET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampus.

EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axonpathfinding.

CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration.

DNA modifications in the mammalian brain.

Patches of disorganization in the neocortex of children with autism.

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