Molecular Mechanisms

Genotype and defects in microtubule-based motility correlate with clinical severity in KIF1A-associated neurological disorder.

Generation of fate patterns via intercellular forces.

CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation.

Integrating barcoded neuroanatomy with spatial transcriptional profiling enables identification of gene correlates of projections.

Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia.

Genetic and morphological estimates of androgen exposure predict social deficits in multiple neurodevelopmental disorder cohorts.

Evaluation of UBE3A antibodies in mice and human cerebral organoids.

The role of GABAergic signalling in neurodevelopmental disorders.

Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior.

Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling.

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