Molecular Mechanisms

Autism risk gene POGZ promotes chromatin accessibility and expression of clustered synaptic genes.

16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis.

Memo1-mediated tiling of radial glial cells facilitates cerebral cortical development.

SCEPTRE improves calibration and sensitivity in single-cell CRISPR screen analysis.

ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research.

Developmental disruption and restoration of brain synaptome architecture in the murine Pax6 neurodevelopmental disease model.

Cortical interneurons in autism.

Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations.

CHD8 regulates gut epithelial cell function and affects autism-related behaviours through the gut-brain axis.

Proximity labeling identifies a repertoire of site-specific R-loop modulators.

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