Complex interplay between cognitive ability and social motivation in predicting social skill: A unique role for social motivation in children with autism.
Circuits, Cognition & Behavior
Diffuse light-sheet microscopy for stripe-free calcium imaging of neural populations.
Cellular-resolution imaging of vestibular processing across the larval zebrafish brain.
Optical trapping in vivo: Theory, practice, and applications.
Altered brain-wide auditory networks in a zebrafish model of fragile X syndrome.
Sound generation in zebrafish with bio-opto-acoustics.
Calcium imaging and the curse of negativity.
Broad frequency sensitivity and complex neural coding in the larval zebrafish auditory system.
Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism.
Cortical encoding of speech in autism
Edward Chang aims to address auditory and speech processing in individuals with epilepsy and autism, with the specific goal of understanding how auditory, phonological and linguistic representations are affected. Understanding how these well-characterized neural representations of speech-relevant acoustic features are impacted in individuals with autism at the level of specific populations of neurons will provide mechanistic insight that may lead to behavioral, pharmacological and neuromodulatory therapies that act in much more targeted ways than is currently possible.
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