Tag: striatum

Impaired reward circuitry during voice processing predicts social communication abilities in autism Vinod Menon and colleagues report that a difference in the activation of a voice-processing network comprising reward and salience detection systems is a distinguishing feature of autism.

The influence of ASD risk genes on corticostriatal circuit development and reinforcement learning Linda Wilbrecht proposes that an inability to appropriately update behavior based on probabilistic feedback represents a core learning deficit in ASD and that specific frontal-striatal circuits may contribute to these…

SFARI Winter 2019 Pilot awardees announced SFARI is pleased to announce that it intends to fund 15 grants in response to the Winter 2019 Pilot Award request for applications (RFA).

Striatal circuit dysfunction in a mouse model of the autism risk gene CACNA1D Anis Contractor will assess how the development of synapses and circuits in the striatum are disrupted in a novel mouse model of autism that harbors a gain-of-function mutation in the…

Neuroscience 2018: Presentations by SFARI Investigators SFARI Investigators will be giving a number of presentations at Neuroscience 2018 in San Diego, CA (November 3–7).

Establishment of specific cortico-basal ganglia circuits by autism-linked protocadherins Hisashi Umemori will use knockout mouse models to identify the roles played by a group of ASD-linked protocadherins in regulating specific cortico-striatal circuits, aiming to reveal novel molecular and circuit…