SFARI 2018 Pilot and Research awardees announced
SFARI is pleased to announce that it intends to fund 36 grants (15 Pilot Awards and 21 Research Awards) in response to the 2018 Pilot and Research Awards request for applications.
Tag: striatum
SFARI spring 2018 science meeting discussed latest developments in autism research
SFARI held its thirteenth science meeting April 8–12, 2018. SFARI investigators, collaborators and foundation staff came together to discuss recent findings in autism genetics, molecular and system-level mechanisms, and clinical studies. In addition to keynote and session presentations, two panels convened investigators to discuss the current state of autism genetics research and the biology of SCN2A, a high-confidence autism risk gene.
FENS Forum 2018: Presentations by SFARI Investigators
SFARI Investigators will be giving a number of presentations at the 11th FENS Forum of Neuroscience in Berlin, Germany (July 7-11).
SFARI 2017 Pilot and Research awardees announced
SFARI is pleased to announce that it has awarded 32 grants (19 Pilot Awards and 13 Research Awards) in response to the 2017 Pilot and Research Awards request for applications (RFA).
The influence of ASD-risk genes on synaptic function in the basal ganglia
Bateup will use genetic mouse models of ASD to investigate the idea that synaptic alterations in the striatum are central to the inflexible behaviors observed in ASD.
Biased spatiotemporal dynamics of striatal circuits impact behavior in autism
The molecular and circuit underpinnings of repetitive behavior dysfunction — a core symptom of ASD — have remained elusive, but it is assumed that they rely on the same basal ganglia circuits that underlie repetitive behavior control and habit formation. The current project aims to investigate, with unprecedented spatial and temporal resolution, the circuit alterations in the striatum that lead to alterations in spontaneous and learned behavioral sequences in ASD.