Tag: epigenetics

January 12, 2023

Cellular resolution multi-omics of white matter tracts in autism

September 06, 2022

SFARI 2022 Pilot awardees announced

June 28, 2022

Functional annotation of gene variants in autism risk genes using DNA methylation signatures

March 16, 2022

Targeted restoration of chromatin regulators as therapeutic interventions for autism

March 15, 2022

Modeling deficiencies in the chromatin modifying enzyme EHMT1 during human neurogenesis using multipurpose degron alleles

December 17, 2021

SFARI 2021 Pilot awardees announced

Neuromuscular junction. Fluorescent confocal light micrograph of the junction between a nerve cell and a muscle (not seen). The axon of the nerve cell (neuron) has been tagged with a blue dye. The axon ends at end plates, which form junctions called synapses with the muscle cells. The end plates have been dyed red here by tagging them with the snake venom alpha-bungarotoxin, which binds to them. When a nerve signal reaches the synapse, it causes the synaptic vesicles to rupture, releasing the neurotransmitter acetylcholine. The protein synaptophysin, found in the vesicles, is dyed green. Acetylcholine binds to receptors on the muscle cells, causing them to contract. Magnification: x120 when printed 10cm wide.

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