SFARI | Search Results for “ben-ari”

The knockout of Synapsin II in mice impairs social behavior and functional connectivity generating an ASD-like phenotype.

Characterizing motor deficits and striatal circuit dynamics in rat models of autism

In this project, Bence Ölveczky aims to garner insight into the neural circuit-level changes associated with autism and how these lead to motor-related manifestations of the condition. To this end, the project will combine long-term continuous neural recordings in the striatum with quantitative measurements of behavior in freely behaving rats.

SFARI Summer 2019 Pilot awardees announced

SFARI is pleased to announce that is intends to fund 12 grants in response to the Summer 2019 Pilot Award request for applications.

SFARI Society for Neuroscience 2019 Social

Join the SFARI science team and leaders in the autism research community for an informal evening of food, drink, conversation and mingling on October 21, 2019, in Chicago.

AGO CLIP reveals an activated network for acute regulation of brain glutamate homeostasis in ischemic stroke.

CRISPR activation-based approach to rescue cellular and behavioral deficits associated with Scn2a haploinsufficiency

Kevin Bender and Nadav Ahituv aim to determine whether upregulation of the remaining functional allele with CRISPR activation-based techniques can rescue cellular and behavioral deficits observed in Scn2a heterozygous mice. If successful, this approach may be applicable to other haploinsufficient genes associated with autism spectrum disorders.

SFARI July 2019 announcements: 2019 Research awardees, new SFARI Gene data release and more

This issue of the SFARI newsletter includes: (1) 2019 Research awardees, (2) SFARI Gene: New data release, (3) Workshop plumbs infancy for autism insights, (4) A Conversation with SFARI Investigator Dan Feldman, (5) Highlights of SFARI-funded research, (6) 2019 Bridge to Independence Award – Request for applications, (7) Winter 2020 Pilot Award – Request for applications, (8) Past webinar: “SFARI Viewer – an online platform to visualize and analyze SFARI genomic data”.

Brief treatment with statin yields long-term benefit in rat model of fragile X syndrome

Peter Kind and colleagues show that brief treatment with lovastatin results in sustained correction of physiological and behavioral deficits in a rat model of fragile X syndrome.

The autism-associated gene Scn2a contributes to dendritic excitability and synaptic function in the prefrontal cortex.

SFARI 2019 Research awardees announced

SFARI is pleased to announce that it intends to fund nine grants in response to the 2019 Research Award request for applications.