Renato Polimanti, Ph.D.

Associate Professor, Yale University

SFARI Investigator Website

Renato Polimanti is a human geneticist with a focus on psychiatry, human evolution, statistical genetics and computational biology. He investigated different aspects of human genetics: predisposition to complex traits, genotype-phenotype correlation of monogenic disorders and human evolutionary biology. His current research interest is to understand the pathogenic mechanisms of behavioral traits and psychiatric disorders using genome-wide data.

Funded Projects

Assessing links between autism spectrum disorder risk alleles with evidence of positive selection and increased cognitive abilities

Awarded: 2017
Award Type: Explorer

SFARI Funded Publications

Polygenic scores for empathy associate with posttraumatic stress severity in response to certain traumatic events. Wendt F.R., Warrier V., Pathak G.A., Koenen K.C., Stein M.B., Krystal J.H., Pietrzak R.H., Gelernter J., Goldfarb E.V., Baron-Cohen S., Polimanti R.

Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Wendt F.R., Pathak G.A., Lencz T., Krystal J.H., Gelernter J., Polimanti R.

Natural selection influenced the genetic architecture of brain structure, behavioral and neuropsychiatric traits. Wendt F.R., Pathak G.A., Overstreet C., Tylee D.S., Gelernter J., Atkinson E.G., Polimanti R.