Molecular Mechanisms

A novel computational biostatistics approach implies impaired dephosphorylation of growth factor receptors as associated with severity of autism.

Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus.

MET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampus.

EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axonpathfinding.

CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration.

DNA modifications in the mammalian brain.

Patches of disorganization in the neocortex of children with autism.

GammaCaMKII shuttles Ca²⁺/CaM to the nucleus to trigger CREB phosphorylation and gene expression.

Topoisomerase 1 inhibition reversibly impairs synaptic function.

CC2D1A regulates human intellectual and social function as well as NF-kappaB signaling homeostasis.

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