Molecular Mechanisms

Dendritic arborization and spine dynamics are abnormal in the mouse model of MeCP2 duplication syndrome.

TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation.

Topoisomerases facilitate transcription of long genes linked to autism.

MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development.

Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons.

AMPD2 regulates GTP synthesis and is mutated in a potentially treatable neurodegenerative brainstem disorder.

Presynaptic neurexin-3 alternative splicing trans-synaptically controls postsynaptic AMPA receptor trafficking.

Alternative splicing of the pituitary adenylate cyclase-activating polypeptide receptor PAC1: Mechanisms of fine tuning of brain activity.

Brain-reactive lgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder.

Mechanisms and therapeutic challenges in autism spectrum disorders: Insights from Rett syndrome.

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