Molecular Mechanisms

The E3 ubiquitin ligase protein associated with Myc (PAM) regulates mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling in vivo through N- and C-terminal domains.

Functional regulation of GABA_A receptors in nervous system pathologies.

Neurexin and neuroligin mediate retrograde synaptic inhibition in Celegans.

Optogenetic control of phosphoinositide metabolism.

CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium.

Modeling human cortical development in vitro using induced pluripotent stem cells.

The emerging role of microRNAs in schizophrenia and autism spectrum disorders.

Synaptic cell adhesion.

Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism.

PtdIns4P synthesis by PI4KIII-alpha at the plasma membrane and its impact on plasma membrane identity.

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