Molecular Mechanisms

FMRP modulates neural differentiation through m⁶A-dependent mRNA nuclear export.

FMRP binding to a ranked subset of long genes is revealed by coupled CLIP and TRAP in specific neuronal cell types.

Prenatal treatment path for Angelman syndrome and other neurodevelopmental disorders.

Differential NOVA2-mediated splicing in excitatory and inhibitory neurons regulates cortical development and cerebellar function.

Widespread alterations in translation elongation in the brain of juvenile Fmr1 knockout mice.

AGO CLIP reveals an activated network for acute regulation of brain glutamate homeostasis in ischemic stroke.

Complex oscillatory waves emerging from cortical organoids model early human brain network development.

Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage.

Placental neurosteroids shape cerebellar development and social behaviour.

Exosomes regulate neurogenesis and circuit assembly.

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