Molecular Mechanisms

Integrating barcoded neuroanatomy with spatial transcriptional profiling enables identification of gene correlates of projections.

Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia.

Genetic and morphological estimates of androgen exposure predict social deficits in multiple neurodevelopmental disorder cohorts.

Evaluation of UBE3A antibodies in mice and human cerebral organoids.

The role of GABAergic signalling in neurodevelopmental disorders.

Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior.

Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling.

A multiplex human pluripotent stem cell platform defines molecular and functional subclasses of autism-related genes.

N-terminal variant Asp14Asn of the human p70 S6 Kinase 1 enhances translational signaling causing different effects in developing and mature neuronal cells.

Identification of neural oscillations and epileptiform changes in human brain organoids.

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