Genetics

Sentinel interaction mapping — a generic approach for the functional analysis of human disease gene variants using yeast.

Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy.

Pleiotropy between language impairment and broader behavioral disorders-an investigation of both common and rare genetic variants.

Dimensional characterizations of gender diversity are associated with higher polygenic propensity for cognitive performance in a neurodiverse sample.

Identification of disease-linked hyperactivating mutations in UBE3A through large-scale functional variant analysis.

Exploring the genetic overlap of suicide-related behaviors and substance use disorders.

S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis.

Creation and evaluation of full-text literature-derived, feature-weighted disease models of genetically determined developmental disorders.

Sex significantly impacts the function of major depression-linked variants in vivo.

Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.

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