Genetics

Pleiotropy between language impairment and broader behavioral disorders-an investigation of both common and rare genetic variants.

Dimensional characterizations of gender diversity are associated with higher polygenic propensity for cognitive performance in a neurodiverse sample.

Identification of disease-linked hyperactivating mutations in UBE3A through large-scale functional variant analysis.

Exploring the genetic overlap of suicide-related behaviors and substance use disorders.

S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis.

Creation and evaluation of full-text literature-derived, feature-weighted disease models of genetically determined developmental disorders.

Sex significantly impacts the function of major depression-linked variants in vivo.

Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.

Autism spectrum disorder/intellectual disability-associated mutations in trio disrupt neuroligin 1-mediated synaptogenesis.

Multivariate genome-wide covariance analyses of literacy, language and working memory skills reveal distinct etiologies.