Perception of cry characteristics in 1-month-old infants later diagnosed with autism spectrum disorder.
Clinical
Development of the emotion dysregulation inventory: A PROMIS®ing method for creating sensitive and unbiased questionnaires for autism spectrum disorder.
Behavioral symptoms of reported abuse in children and adolescents with autism spectrum disorder in inpatient settings.
Characterization of medication use in a multicenter sample of pediatric inpatients with autism spectrum disorder.
Predictors of inpatient psychiatric hospitalization for children and adolescents with autism spectrum disorder.
Insistence on sameness and broader autism phenotype in simplex families with autism spectrum disorder.
A longitudinal study of parent-reported sensory responsiveness in toddlers at-risk for autism.
Identifying EEG biomarkers of treatment outcome
Previous clinical trials of arbaclofen for the treatment of autism and fragile X syndrome have suffered from large placebo effects and non-optimal outcome measures. Here, Emily Jones and her colleagues propose to incorporate EEG measures into two ongoing arbaclofen clinical trials in order to search for sensitive and predictive biomarkers of treatment efficacy that correlate with behavioral outcomes.
Combining pivotal response treatment with intranasal oxytocin to improve social reciprocity in children with ASD
Denis Sukhodolsky and Kevin Pelphrey will perform a randomized clinical trial of oxytocin to determine if it can enhance responses to Pivotal Response Training in young children with autism. Functional magnetic resonance brain imaging and eye tracking measures will be studied in conjunction with key behavioral outcomes. This study will aid in the development of more precise treatments for children with ASD that are guided by objective neurobiological markers.
The severe end of the spectrum: Insights and opportunities from the Autism Inpatient Collection (AIC).
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