SFARI | Topic: Clinical

Relationship between childhood obesity and autism spectrum disorder varies by child’s age and parents’ weight status in a sample of sibling dyads.

Digit ratio (2D:4D) and maternal testosterone-to-estradiol ratio measured in early pregnancy.

Evaluation of data imputation strategies in complex, deeply-phenotyped data sets: The case of the EU-AIMS Longitudinal European Autism Project.

Co-occurring ADHD symptoms in autistic adults are associated with less independence in daily living activities and lower subjective quality of life.

Examining treatment outcomes across contexts: How do child baseline characteristics impact measurement of treatment response?

Complexity analysis of head movements in autistic toddlers.

COVID-19 in pregnancy and early childhood: COPE study

The COPE study aims to investigate how SARS-CoV-2 affects pregnancy outcome and maternal and child health including follow-up of the child’s neurocognitive development and neuropsychiatric health. Neuropsychiatric diagnoses will be collected from the mandatory Swedish patient register, while milder developmental delays or deviations will be captured by the Ages and Stages Questionnaire, delivered as part of this study.

Telehealth diagnosis of autism spectrum disorder through clinical cases.

Premature primary tooth eruption in cognitive/motor-delayed ADNP-mutated children.

A registry for clinical and functional data for variants in the GRIN gene family

GRIN disorders are rare neurodevelopmental genetic conditions that alter genes that encode NMDA receptor subunits. Stephen Traynelis and colleagues plan to understand the natural history, incidence and full spectrum of clinical and functional consequences of variation that lead to GRIN disorders. This multi-dimensional dataset will be compiled and shared in a fashion that will help to catalyze the development of new therapeutic treatment strategies.