Tag: SHANK3

Screening for convergence of axonal dysfunction across diverse mouse models of autism John Huguenard has preliminary data to suggest that neuronal axons don't develop normally in two mouse models of ASD that result from maternal immune activation. In the current proposal, Huguenard…

SFARI fall 2018 science meeting highlighted recent findings in autism research SFARI held its fourteenth science meeting September 30–October 2, 2018. SFARI investigators, collaborators and foundation staff came together to discuss recent findings in autism genetics, molecular and system-level mechanisms, as…

In vivo calcium dynamics in dendritic spines of Shank3 and Scn2a mutant mouse models of autism Converging lines of evidence suggest that dendritic spine pathology is a common feature in ASD. Alex Kwan will use advanced optical imaging methods in awake behaving mice to determine how…

Coordinating animal- and human-based research on sensory alterations in autism spectrum disorders On September 25, 2018, SFARI convened a workshop with the aims of discussing current research on sensory processing in autism and bringing together investigators that conduct animal- and human-based studies…

SFARI Winter 2019 Pilot awardees announced SFARI is pleased to announce that it intends to fund 15 grants in response to the Winter 2019 Pilot Award request for applications (RFA).

SFARI workshop highlighted chromatin-associated proteins and autism risk On April 17, 2018, molecular neuroscientists and geneticists gathered at the Simons Foundation for a workshop on the role of chromatin-associated proteins in autism spectrum disorder. The workshop discussed the…