Tag: SHANK3

January 25, 2023

Neural basis for observational learning in autism mouse models

October 11, 2022

Critical period plasticity underlying complex learning in autism rat models

August 31, 2022

New DYRK1A and GRIN2B zebrafish models added to SFARI resources

August 16, 2022

A bidirectional switch affecting phosphorylation of Shank3 influences homeostatic synaptic plasticity By Azra Jaferi

August 09, 2022

Understanding insomnia in the autism spectrum using mouse models

December 17, 2021

SFARI 2021 Pilot awardees announced

Neuromuscular junction. Fluorescent confocal light micrograph of the junction between a nerve cell and a muscle (not seen). The axon of the nerve cell (neuron) has been tagged with a blue dye. The axon ends at end plates, which form junctions called synapses with the muscle cells. The end plates have been dyed red here by tagging them with the snake venom alpha-bungarotoxin, which binds to them. When a nerve signal reaches the synapse, it causes the synaptic vesicles to rupture, releasing the neurotransmitter acetylcholine. The protein synaptophysin, found in the vesicles, is dyed green. Acetylcholine binds to receptors on the muscle cells, causing them to contract. Magnification: x120 when printed 10cm wide.

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