Male, but not female, 16p11.2 deletion mice show deficits in reward learning By assessing the 16p11.2 deletion autism mouse model, Ted Abel and colleagues uncover male-specific vulnerabilities in striatal signaling and reward function.
Cellular and molecular mechanisms of sex bias in maternal immune activation-induced autism Lukens and Zunder will utilize transcriptomics, mass cytometry and data-driven science to uncover cellular and molecular underpinnings of sex bias in an MIA model of autism.
IMFAR 2017: Presentations by SFARI Investigators Presentations that will be given by SFARI Investigators at the 2017 International Meeting for Autism Research (IMFAR) in San Francisco (May 10-13) are highlighted.
SFARI 2016 Pilot and Research awardees announced SFARI is pleased to announce that it has awarded 27 grants (21 Pilot Awards and 6 Research Awards) in response to the 2016 Pilot and Research Awards request for applications.
Genetic mechanisms underlying physical trait differences between males and females contribute to sex bias in autism By examining SNPs from ASD datasets, Lauren Weiss finds that genetic mechanisms regulating general sex differences, such as height and weight, contribute to autism risk.
Exploring sex differences in autism via the NRXN1 knockout rat Autism spectrum disorder (ASD) is diagnosed in boys 4-5 times more frequently than in girls. Many factors contribute to this gender bias, but the origins of the biological factors remain…