Assessing network and synaptic communication in the hippocampus of behaving Fmr-1 null mice, André Fenton and colleagues showed altered network communication linked to behavioral alterations in fragile X syndrome.
SFARI is pleased to announce that it has awarded 32 grants (19 Pilot Awards and 13 Research Awards) in response to the 2017 Pilot and Research Awards request for applications (RFA).
A selection of presentations that will be given by past and current SFARI Investigators at Neuroscience 2017 in Washington, D.C., (November 11–15) is highlighted.
Choi proposes to use the MIA mouse model with a discrete, functionally relevant lesion in the primary somatosensory cortex to elucidate neural circuits that modulate ASD-associated behaviors.
The molecular and circuit underpinnings of repetitive behavior dysfunction — a core symptom of ASD — have remained elusive, but it is assumed that they rely on the same basal ganglia circuits that underlie repetitive behavior control and habit formation. The current project aims to investigate, with unprecedented spatial and temporal resolution, the circuit alterations in the striatum that lead to alterations in spontaneous and learned behavioral sequences in ASD.
SFARI Investigator Sung Han discusses his lab’s work and how the Bridge to Independence Award helped him launch his independent career in autism research.