
SFARI is helping to make rat models of high-risk autism genes available to the research community.

SFARI is helping to make rat models of high-risk autism genes available to the research community.

Today, we’re announcing our annual request for applications (RFA) for SFARI Pilot and Research Awards. Letters of intent (LOIs), the short statements that precede full applications, are due no later than 9 October, 2015. As we do every year, we’ve updated this column to provide a better picture of how the SFARI science team makes decisions on research proposals.

The Simons Variation in Individuals Project (Simons VIP) is studying individuals with recurrent genetic variants that increase autism risk.

A number of autism risk factors converge on one cellular pathway: abnormal remodeling of the cell's structural systems through the signaling protein Rho, says SFARI’s associate director for research, Alan Packer.

SFARI is helping to make mouse models of high-risk autism genes and copy number variants available to the research community.