SFARI

SFARI Gene is an evolving database for the autism research community that is centered on genes implicated in autism susceptibility.

SFARI Base provides approved researchers with access to data and biospecimens from the SSC, Simons Searchlight, SPARK and Autism Inpatient Collection.

The Simons Simplex Collection (SSC) contains genetic and phenotypic data from nearly 3,000 families with a child affected by autism.

The Simons Variation in Individuals Project (Simons VIP) is studying individuals with recurrent genetic variants that increase autism risk.

In 2021, SFARI launched the Autism Rat Models Consortium (ARC) RFA. Grants supported through this RFA use SFARI autism rat models to investigate the biology of autism risk genes, with a particular focus on complex behaviors and their underlying neural circuits.

SFARI is helping to make iPS cell lines derived from individuals who participated in the SSC and Simons Searchlight available to researchers.

Simons Searchlight is studying individuals with recurrent genetic variants associated with autism and related neurodevelopmental disorders.

A number of visualization and analysis tools are available to explore genetic and phenotypic data from the SSC, Simons Searchlight and SPARK.

SFARI is helping to make rat models of high-risk autism genes available to the research community.

SFARI is helping to make mouse models of high-risk autism genes and copy number variants available to the research community.