Research Articles

Mutational bias and the protein code shape the evolution of splicing enhancers.

FMRP links optimal codons to mRNA stability in neurons.

Directed information exchange between cortical layers in macaque V1 and V4 and its modulation by selective attention.

MTSplice predicts effects of genetic variants on tissue-specific splicing.

Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks.

Clustering by phenotype and genome-wide association study in autism.

ATP synthase c-subunit leak causes aberrant cellular metabolism in fragile X syndrome.

A multidimensional precision medicine approach identifies an autism subtype characterized by dyslipidemia.

Predicting functional effects of missense variants in voltage-gated sodium and calcium channels.

Input-output relationship of CA1 pyramidal neurons reveals intact homeostatic mechanisms in a mouse model of fragile X syndrome.