Saturated reconstruction of living brain tissue.
Preprints
ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis.
Oxytocin attenuates microglial activation and restores social and non-social memory in the APP/PS1 mouse model of Alzheimer’s disease.
Balanced chromosomal rearrangements offer insights into coding and noncoding genomic features associated with developmental disorders.
Fine-grained topographic organization within somatosensory cortex during resting-state and emotional face-matching task and its association with ASD traits.
Clarity increases sensitivity and specificity of fluorescence immunostaining in long-term archived human brain tissue.
Convergent coexpression of autism associated genes suggests some novel risk genes may not be detectable in large-scale genetic studies.
Autism in gifted youth is associated with low processing speed and high verbal ability.
EphB1 controls proper long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells.
SETBP1 variants outside the degron disrupt DNA-binding and transcription independent of protein abundance to cause a heterogeneous neurodevelopmental disorder.
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