Preprints

A new theoretical framework jointly explains behavioral and neural variability across subjects performing flexible decision-making.

Transcriptional diversity in synaptic gene sets is sufficient to discriminate cortical neuronal identity.

Rubella virus tropism and single cell responses in human primary tissue and microglia-containing organoids.

In vivo proximity ligation reveals endogenous candidate interactors of neurexin’s intracellular domain.

Repeat polymorphisms in non-coding DNA underlie top genetic risk loci for glaucoma and colorectal cancer.

High body mass polygenic risk in mothers enhances de novo functional mutations in epigenetic and microtubule gene pathways in their offspring with autism spectrum disorder.

GATK-gCNV: A rare copy number variant discovery algorithm and its application to exome sequencing in the UK Biobank.

Rapid specification of human pluripotent stem cells to functional astrocytes.

Isoform-level transcriptome-wide association uncovers extensive novel genetic risk mechanisms for neuropsychiatric disorders in the human brain.

Polygenic architecture of rare coding variation across 400,000 exomes.