Tunable, proteolytic dosage control of CRISPR-Cas systems enables precise gene therapy for dosage sensitive disorders.
Preprints
Molecular and cellular dynamics of the developing human neocortex at single-cell resolution.
Phenotypical divergence between self-reported and clinically ascertained autism.
Polygenic and developmental profiles of autism differ by age at diagnosis.
Human-specific gene expansions contribute to brain evolution.
Early developmental origins of cortical disorders modeled in human neural stem cells.
Decomposition of phenotypic heterogeneity in autism reveals distinct and coherent genetic programs.
Cell type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development.
Identification of moderate effect size genes in autism spectrum disorder through a novel gene pairing approach.
Contribution of autosomal rare and de novo variants to sex differences in autism.
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